• Stepan JG, Lovecchio FC, Premkumar A, Kahlenberg CA, Albert TJ, Baurley JW, Nwachukwu BU. Development of an Institutional Opioid Prescriber Education Program and Opioid-Prescribing Guidelines: Impact on Prescribing Practices. J Bone Joint Surg Am. 2019. | https://www.ncbi.nlm.nih.gov/pubmed/30601411

  • Panagiotou OA, Schuit E, Munafò MR, Bennett DA, Bergen AW, David SP. Smoking Cessation Pharmacotherapy Based on Genetically-Informed Biomarkers: What is the Evidence?. Nicotine Tob Res. 2019. | https://www.ncbi.nlm.nih.gov/pubmed/30690475

  • Duffy ME, Rogers ML, Joiner TE, et al. An investigation of indirect effects of personality features on anorexia nervosa severity through interoceptive dysfunction in individuals with lifetime anorexia nervosa diagnoses. Int J Eat Disord. 2019;52(2):200-205. | https://www.ncbi.nlm.nih.gov/pubmed/30636025



  • McMahan C, Baurley J, Bridges W, et al. A Bayesian hierarchical model for identifying significant polygenic effects while controlling for confounding and repeated measures. Stat Appl Genet Mol Biol. 2017. | https://www.ncbi.nlm.nih.gov/pubmed/29140792

  • Schuit E, Panagiotou OA, Munafò MR, Bennett DA, Bergen AW, David SP. Pharmacotherapy for smoking cessation: effects by subgroup defined by genetically informed biomarkers. Cochrane Database Syst Rev. 2017;9:CD011823. | https://www.ncbi.nlm.nih.gov/pubmed/28884473

  • Saccone NL, Baurley JW, Bergen AW, et al. The Value of Biosamples in Smoking Cessation Trials: A Review of Genetic, Metabolomic, and Epigenetic Findings. Nicotine Tob Res. 2017. |  https://www.ncbi.nlm.nih.gov/pubmed/28472521

  • Chen LS, Zawertailo L, Piasecki TM, et al. Leveraging genomic data in smoking cessation trials in the era of Precision Medicine: Why and how. Nicotine Tob Res. 2017. | https://www.ncbi.nlm.nih.gov/pubmed/28498934

  • Schuit E, Panagiotou OA, Munafò MR, Bennett DA, Bergen AW, David SP. Pharmacotherapy for smoking cessation: effects by subgroup defined by genetically informed biomarkers. Cochrane Database Syst Rev. 2017;9:CD011823. |  https://www.ncbi.nlm.nih.gov/pubmed/28884473

  • Hinney A, Kesselmeier M, Jall S, et al. Evidence for three genetic loci involved in both anorexia nervosa risk and variation of body mass index. Mol Psychiatry. 2017;22(2):192-201. | https://www.ncbi.nlm.nih.gov/pubmed/27184124


  • David SP, Wang A, Kapphahn K, et al. Gene by Environment Investigation of Incident Lung Cancer Risk in African-Americans. EBioMedicine. 2016;4:153-61. | https://www.ncbi.nlm.nih.gov/pubmed/26981579

  • A Hinney, M Kesselmeier, S Jall, A-L Volckmar, M Föcker, J Antel, GCAN, WTCCC3, I M Heid, T W Winkler, GIANT, S F A Grant, EGG, Y Guo, A W Bergen, W Kaye, W Berrettini, H Hakonarson, Price Foundation Collaborative Group, Children’s Hospital of Philadelphia/Price Foundation, B Herpertz-Dahlmann, M de Zwaan, W Herzog, S Ehrlich, S Zipfel, K M Egberts, R Adan, M Brandys, A van Elburg, V Boraska Perica, C S Franklin, M H Tschöp, E Zeggini, C M Bulik, D Collier, A Scherag, T D Müller and J Hebebrand. Evidence for three genetic loci involved in both anorexia nervosa risk and variation of body mass index. Molecular Psychiatry 22, 192-201 (February 2017) | doi:10.1038/mp.2016.71. |

  • James W. Baurley, PhD; Christopher K. Edlund, MS; Carissa I. Pardamean, MS; David V. Conti, PhD; Ruth Krasnow, MA; Harold S. Javitz, PhD; Hyman Hops, PhD; Gary E. Swan, PhD; Neal L. Benowitz, MD; Andrew W. Bergen, PhD. Genome-Wide Association of the Laboratory-Based Nicotine Metabolite Ratio in Three Ancestries. Nicotine Tob Res (2016) 18 (9): 1837-1844. DOI: https://doi.org/10.1093/ntr/ntw117. | https://www.ncbi.nlm.nih.gov/pubmed/27113016

  • Pardamean, B., Baurley, J.W., Pardamean, C.I. et al. Changing colorectal cancer trends in Asians. Int J Colorectal Dis (2016) 31: 1537. doi:10.1007/s00384-016-2564-z |

  • Sean P. David, Ange Wang, Kristopher Kapphahn, Haley Hedlin, Manisha Desai,Michael Henderson, Lingyao Yang, Kyle M. Walsh, Ann G. Schwartz, John K. Wiencke, Margaret R. Spitz, Angela S. Wenzlaff, Margaret R. Wrensch, Charles B. Eaton, Helena Furberg, W. Mark Brown, Benjamin A. Goldstein, Themistocles Assimes, Hua Tang, Charles L. Kooperberg, Charles P. Quesenberry, Hilary Tindle, Manali I. Patel, Christopher I. Amos, Andrew W. Bergen, Gary E. Swan,and Marcia L. Stefanickb. Gene by Environment Investigation of Incident Lung Cancer Risk in African-Americans. EBioMedicine. 2016 Feb; 4: 153–161. |

  • Baurley JW, Edlund CK, Pardamean CI, Conti DV, Bergen AW. Smokescreen: a targeted genotyping array for addiction research. BMC Genomics. 2016, 17:145. |


  • Bergen AW, Krasnow R, Javitz HS, Swan GE, Li MD, Baurley JW, Chen X, Murrelle L, Zedler B. Total Exposure Study Analysis consortium: a cross-sectional study of tobacco exposures. BMC Public Health. 2015 Sep 7;15(1):866. | http://www.ncbi.nlm.nih.gov/pubmed/26346437

  • Bergen AW, Michel M, Nishita D, Krasnow R, Javitz HS, Conneely KN, Lessov-Schlaggar CN, Hops H, Zhu AZ, Baurley JW, McClure JB, Hall SM, Baker TB, Conti DV, Benowitz NL, Lerman C, Tyndale RF, Swan GE; Transdisciplinary Research in Cancer of the Lung Research Team.Drug Metabolizing Enzyme and Transporter Gene Variation, Nicotine Metabolism, Prospective Abstinence, and Cigarette Consumption. PLoS One. 2015 Jul 1;10(7). | http://www.ncbi.nlm.nih.gov/pubmed/26132489


  • Figueiredo JC, Ly S, Raimondi H, Magee K, Baurley JW, Sanchez-Lara PA, Ihenacho U, Yao C, Edlund CK, van den Berg D, Casey G, DeClerk YA, Samet JM, Magee W 3rd. Genetic risk factors for orofacial clefts in Central Africans and Southeast Asians. Am J Med Genet A. 2014 Oct;164A(10):2572-80. | http://www.ncbi.nlm.nih.gov/pubmed/25099202


  • Bergen AW, Javitz HS, Krasnow R, Edlund CK, Swan GE. Nicotinic acetylcholine receptor variation and response to smoking cessation therapies. Pharmacogenet Genomics 2013, 23(2):94-103. | http://www.ncbi.nlm.nih.gov/pubmed/23249876


  • Baurley JW, Edlund CK, Pardamean B. Cloud Computing for Genome-Wide Association Analysis. Advances in Intelligent and Soft Computing 2012, 144:377-83.

  • Myers RA, Himes BE, Gignoux CR…Baurley J…Ober C. Further replication studies of the EVE Consortium meta-analysis identifies 2 asthma risk loci in European Americans.J Allergy Clin Immunol 2012, 130(6):1294-301. | http://www.ncbi.nlm.nih.gov/pubmed/23040885

  • Cozen W, Li D, Best T…Edlund CK…Onel K. A genome-wide meta-analysis of nodular sclerosing Hodgkin lymphoma identifies risk loci at 6p21.32. Blood 2012, 119(2):469-75. | http://www.ncbi.nlm.nih.gov/pubmed/22086417

  • Leng S, Stidley CA, Liu Y, Edlund CK…Belinsky SA. Genetic determinants for promoter hypermethylation in the lungs of smokers: a candidate gene-based study. Cancer Res. 2012, 72(3):707-15. | http://www.ncbi.nlm.nih.gov/pubmed/22139380

  • Levine AJ, Ihenacho U, Lee W…Edlund CK…Haile RW. Genetic variation in insulin pathway genes and distal colorectal adenoma risk. Int J Colorectal Dis 2012, 27(12):1587-95. | http://www.ncbi.nlm.nih.gov/pubmed/22645077

  • Stewart SE, Yu D, Scharf JM…Edlund CK…Pauls DL. Genome-wide association study of obsessive-compulsive disorder.Mol Psychiatry 2012. | http://www.ncbi.nlm.nih.gov/pubmed/22889921

  • Scharf JM, Yu D, Mathews CA…Edlund CK…Pauls DL. Genome-wide association study of Tourette’s syndrome. Mol Psychiatry 2012. | http://www.ncbi.nlm.nih.gov/pubmed/22889924


  • Haiman CA, Chen GK, Vachon CM…Edlund CK…Couch FJ. A common variant at the TERT-CLPTM1L locus is associated with estrogen receptor-negative breast cancer. Nat Genet.2011, 43(12): 1210-4. | http://www.ncbi.nlm.nih.gov/pubmed/22037553

  • Peters U, Hutter CM, Hsu L…Edlund CK…Casey G. Meta-analysis of new genome-wide association studies of colorectal cancer risk. Human Genetics 2012, 131(2): 217-34. |

  • Torgerson DG, Ampleford EJ, Chiu GY…Baurley JW…Nicolae DL. Meta-analysis of genome-wide association studies of asthma in ethnically diverse North American populations.Nature Genetics 2011, 43(9):887-92. | http://www.ncbi.nlm.nih.gov/pubmed/21804549

  • Pearce CL, Doherty JA, Van Den Verg DJ…Edlund CK…Wu AH. Genetic variation in insulin-like growth factor 2 may play a role in ovarian cancer risk. Human Molecular Genetics 2011, 20(11):2263-72. | http://www.ncbi.nlm.nih.gov/pubmed/21422097

  • Figueiredo JC, Lewinger JP, Song C, Campbell PT, Conti DV, Edlund CK, Duggan DJ, Rangrej J, Lemire M, Hudson T, Zanke B, Cotterchio M, Gallinger S, Jenkins MA, Hopper J, Haile RW, Newcomb PA, Potter JD, Baron JA, Le Marchand L, Casey G. Genotype-Environment Interactions in MSS/MSI-Low Colorectal Cancer: Results from a Genome-Wide Association Study. Cancer Epidemiology, Biomarkers & Prevention 2011, 20(5):758-66. |

  • Levine AJ, Lee W, Figueiredo JC, Conti DV, Vandenberg DJ, Davis BD, Edlund CK, Henning SM, Heber D, Stern MC, Haile RW. Variation in folate pathway genes and distal colorectal adenoma risk: a sigmoidoscopy-based case-control study.Cancer Causes Control 2011, 22(4):541-52. | http://www.ncbi.nlm.nih.gov/pubmed/21274745


  • Hunninghake GM, Soto-Quirós ME, Avila L…Baurley JW…Celedón JC. TSLP polymorphisms are associated with asthma in a sex-specific fashion. Allergy 2010, 65(12):1566-75. |

  • DeWan AT, Triche EW, Xu X…Baurley JW…Bracken MB. PDE11A associations with asthma: results of a genome-wide association scan. J Allergy Clin Immunol. 2010, 126(4):871-873. |

  • Baurley JW, Conti DV, Gauderman WJ, Thomas DC. Discovery of complex pathways from observational data.Stat Med 2010, 29(19):1998-2011. | http://www.ncbi.nlm.nih.gov/pubmed/20683892

  • Wilson MA, Baurley JW, Thomas DC, Conti DV. Complex system approaches to genetic analysis Bayesian approaches.Adv Genet 2010, 72:47-71. | http://www.ncbi.nlm.nih.gov/pubmed/21029848

  • Wazni O, Epstein LM, Carrillo RG…Ervin CM, Wilkoff BL. Lead extraction in the contemporary setting: the LExICon study: an observational retrospective study of consecutive laser lead extractions. J Am Coll Cardiol. 2010 Feb 9;55(6):579-86. Erratum in: J Am Coll Cardiol. 2010 Mar 9;55(10):1055. | http://www.ncbi.nlm.nih.gov/pubmed/20152562


  • Schildkraut JM, Goode EL, Clyde MA…Edlund CK…Australian Ovarian Cancer Study Group. Single Nucleotide Polymorphism in the TP53 Region and Susceptibility to Invasive Epithelial Ovarian Cancer. Cancer Research 2009, 69(6):2349-57. | http://www.ncbi.nlm.nih.gov/pubmed/19276375

  • Pearce CL, Near AM, Van Den Berg DJ…Edlund CK…Australian Ovarian Cancer Study Group on behalf of the Ovarian Cancer Association Consortium. Validating genetic risk associations for ovarian cancer through the international Ovarian Cancer Association Consortium. British Journal of Cancer 2009, 100(2):412-20. | http://www.ncbi.nlm.nih.gov/pubmed/19127255

  • Thomas DC, Conti DV, Baurley J, Nijhout F, Reed M, Ulrich CM. Use of pathway information in molecular epidemiology.Hum Genomics 2009, 4(1):21-42. | http://www.ncbi.nlm.nih.gov/pubmed/21072972

  • Himes BE, Hunninghake GM, Baurley JW…Weiss ST. Genome-wide association analysis identifies PDE4D as an asthma-susceptibility gene. Am J Hum Genet. 2009, 84(5):581-93. |

  • Engelman CD, Baurley JW, Chiu YF, Joubert BR, Lewinger JP, Maenner MJ, Murcray CE, Shi G, Gauderman WJ. Detecting gene-environment interactions in genome-wide association data. Genet Epidemiol. 2009, 33 Suppl 1: S68-73. | http://www.ncbi.nlm.nih.gov/pubmed/19924704


  • Thomas DC, Baurley JW, Brown EE, Figueiredo JC, Goldstein A, Hazra A, Wilson RT, Rothman N; American Association for Cancer Research. Approaches to complex pathways in molecular epidemiology: summary of a special conference of the American Association for Cancer Research. Cancer Res.2008, 68(24):10028-30. | http://www.ncbi.nlm.nih.gov/pubmed/19074865

  • Palmieri RT, Wilson MA, Iversen ES…Edlund CK…Australian Ovarian Cancer Study Group. Polymorphism in the IL18 Gene and Epithelial Ovarian Cancer in Non-Hispanic White Women. Cancer Epidemiology, Biomarkers & Prevention 2008, 17(12):3567-72. | http://www.ncbi.nlm.nih.gov/pubmed/19064572

  • Edlund CK, Lee WH, Li D, Van Den Berg DJ, Conti DV. Snagger: a user-friendly program for incorporating additional information for tagSNP selection. BMC Bioinformatics 2008, 9:174 | http://www.ncbi.nlm.nih.gov/pubmed/18371222

  • Winstein C, Pate P, Ge T, Ervin C, Baurley J, Sullivan KJ, Underwood SJ, Fowler EG, Mulroy S, Brown DA, Kulig K, Gordon J, Azen SP; Physical Therapy Clinical Research Network (PTClinResNet). The physical therapy clinical research network (PTClinResNet): methods, efficacy, and benefits of a rehabilitation research network. Am J Phys Med Rehabil. 2008, 87(11):937-50. | http://www.ncbi.nlm.nih.gov/pubmed/18174846


  • Lewinger JP, Conti DV, Baurley JW, Triche TJ, Thomas DC. Hierarchical Bayes prioritization of marker associations from a genome-wide association scan for further investigation.Genet Epidemiol. 2007, 31(8):871-82. | http://www.ncbi.nlm.nih.gov/pubmed/17654612

  • Selkowitz DM, Kulig K, Poppert EM…Ervin C, Powers CM, and Physical Therapy Clinical Research Network (PTClinResNet): The immediate and long-term effects of exercise and patient education on physical, functional, and quality-of-life out come measures after single-level lumbar microdiscectomy: a randomized controlled trial protocol. BMC Musculoskeletal Disorders 2006 , 7:70. | https://www.ncbi.nlm.nih.gov/pubmed/16934143


  • Cole SR, Hernan MA, Robins JM…Ervin CM…Munoz A. Effect of highly active antiretroviral therapy on time to acquired immunodeficiency syndrome or death using marginal structural models. American Journal of Epidemiology.158(7):687-94, 2003 Oct 1.


  • Levine AJ, Harper JM, Ervin CM…Haile RW. Serum 25-hydroxyvitamin D, dietary calcium intake, and distal colorectal adenoma risk. Nutrition & Cancer. 39(1):35-41, 2001.


  • Levine AJ, Siegmund KD, Ervin CM…Haile RW. The methylenetetrahydrofolate reductase 677C–>T polymorphism and distal colorectal adenoma risk. Cancer Epidemiology, Biomarkers & Prevention. 9(7):657-63, 2000 July.


  • Haile RW, Witte JS, Gold M…Ervin C… Wang G. The health effects of swimming in ocean water contaminated by storm drain runoff. Epidemiology. 10(4):355-63, 1999 July.


We include research here when at least one author was affiliated with BioRealm as of the date of publication, or is a BioRealm founder.